Lp(a) in Clinical Practice
Lipoprotein(a), or Lp(a), is an inherited risk factor linked to atherosclerotic cardiovascular disease and aortic valve disease. This course provides a focused, practical review for clinicians. You will learn how Lp(a) is structured, how it is inherited, and how it contributes to cardiovascular risk. The course outlines guideline-based indications for testing, explains how to order and interpret results in nmol/L or mg/dL, and supports clear patient communication. You will also integrate Lp(a) into risk management plans, including LDL lowering strategies and referral pathways, and review the clinical relevance of emerging Lp(a)-targeted therapies.
By the end of this course, you will be able to:
- Describe the structure and atherogenic mechanisms of lipoprotein(a).
- Explain how elevated Lp(a) increases cardiovascular and aortic stenosis risk.
- Apply Lp(a) testing results to clinical risk stratification decisions.
- Describe current and emerging strategies to reduce Lp(a)-associated cardiovascular risk.
Listen to the companion podcast episode for this course.
Course Content
Module 1: Understanding Lp(a) – Foundations and Pathophysiology
Module 2: Lp(a) as a Risk Factor – Clinical Implications
Module 3: Testing and Interpretation – Applying Lp(a) in Practice
Module 4: Management Strategies and Future Directions
Learner Reviews
Funding for this course was provided by unrestricted educational grants from
